Adiponectin Regulates the Development and Progression of MCA-Induced Sarcoma in Mice
نویسندگان
چکیده
progression of mouse sarcoma. The results indicated that adiponectin deficiency increased the tumor incidence; in addition, the occurrence of sarcoma was earlier in contrast with the wild type (WT) mice. It is worth mentioning, after the sarcomas formation, adiponectin deficiency had been shown to have the effect of suppressing tumor growth. Mortality rates of the adiponectin-deficient mice with sarcoma were lower than the rates of the WT control group. Our data suggested that adiponectin may have inhibiting effects on the sarcomas formation, whereas, promote the tumor growth during the sarcomas progression.
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